Tuesday 21 August 2012

Nanonephrology

Nanonephrology is a branch of nanomedicine and nanotechnology that seeks to use nano-materials and nano-devices for the diagnosis, therapy, and management of renal diseases. It includes the following goals:

1.    the study of kidney protein structures at the atomic level
2.    nano-imaging approaches to study cellular processes in kidney cells
3.    nano medical treatments that utilize nanoparticles to treat various kidney diseases
Advances in Nanonephrology are expected to be based on discoveries in the above areas that can provide nano-scale information on the cellular molecular machinery involved in normal kidney processes and in pathological states. By understanding the physical and chemical properties of proteins and other macromolecules at the atomic level in various cells in the kidney, novel therapeutic approaches can be designed to combat major renal diseases. The nano-scale artificial kidney is a goal that many physicians dream of. Nano-scale engineering advances will permit programmable and controllable nano-scale robots to execute curative and reconstructive procedures in the human kidney at the cellular and molecular levels. Designing nanostructures compatible with the kidney cells and that can safely operate in vivo is also a future goal. The ability to direct events in a controlled fashion at the cellular nano-level has the potential of significantly improving the lives of patients with kidney diseases.

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